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PERMEAVITS

€38.50

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Specific complex Immunity Intestinal flora

Preserve Your Intestinal Barrier

Support the intestinal barrier with MicrobiomeX® and Mucosave®.
Clinical results validated on MicrobiomeX® and Mucosave®.
Maintains normal mucous membranes thanks to vitamin A
Natural formulation rich in hesperidin, naringin and bromelain

The benefits

Intestinal mucosa Vitamin A helps maintain normal mucous membranes.
Digestion Olive contributes to the functions of the intestinal tract.

Product qualities

Pullulan capsule (100% vegetable)
Casein-free, gluten-free, lactose-free
No preservatives, no pesticides, no artificial colours or flavours
Recycling
MicrobiomeX®
Mucosave® FG

Description

Nutritional information

NUTRITIONAL INFORMATION

3 CAPSULES

AR%*

Microbiomex®

Orange & grapefruit extract (94:6)

85% hesperidin & 5% naringin

Mucosave®

Prickly pear 35% & olive 25% extracts

Bromelain 5000 GDU/g

20% beta-carotene

Of which natural vitamin A

500mg

400mg

24mg

800ug

100

* Intake Reference (directive 2008/100/CE modifiant -> arrêté 08.01.1992)

Strengthen Your Intestinal Barrier

Perméavits is a dietary supplement designed to support the intestinal barrier, thanks to the action of vitamin A, which contributes to the maintenance of normal mucous membranes. It also helps improve digestive comfort, supported by the properties of olive, which contributes to the functions of the intestinal tract, providing essential support for balanced digestion. Stress, poor diet, and a sedentary lifestyle weaken digestive health, leading to discomforts such as bloating and reflux. Perméavits helps the proper functioning of digestive mucous membranes and aids in maintaining a healthy microbiome balance.

Key Ingredients for Enhanced Intestinal Health

MicrobiomeX®: This citrus extract, rich in flavonoids, is metabolized by the gut microbiome to support mucosal health and stimulate the production of short-chain fatty acids (SCFAs) such as butyrate, which is essential for the optimal functioning of the intestinal mucosa.

The graph shows an increase in Clostridium cluster XIVa after 12 weeks of treatment with MicrobiomeX®.[5] This bacterial group, associated with better intestinal health, saw an increase of 43.9% in participants consuming MicrobiomeX®, compared to only 15.9% in the placebo group. Although this difference was not statistically significant, it highlights a positive effect of the supplement on modulating the gut microbiome, contributing to better balance and intestinal barrier defense.

Mucosave®: This complex combines polysaccharides from Opuntia (prickly pear) and biophenols from Olea europaea (olive). Scientifically, these ingredients have been chosen for their distinct properties: the polysaccharides from prickly pear act by forming a protective film on the mucosa. Olive extract, on the other hand, has a validated health claim: it contributes to the proper functioning of the intestinal tract. This effect is linked to olive biophenols, which regulate digestive functions. A randomized, controlled study showed that Mucosave® improves gastrointestinal quality of life after 8 weeks.[2] The study measured several parameters such as abdominal pain, constipation, and gastroesophageal reflux.

The graph reinforces the data by showing an improvement in gastrointestinal quality of life for each individual response after 8 weeks. The green bars (Mucosave® after 8 weeks) are significantly higher than the orange bars (placebo), indicating a reduction in digestive manifestations. Participants also reported a 70% reduction in gastrointestinal discomfort.

Product Details

Conditionnement: 60 capsules
Composition: Microbiomex® (orange and grapefruit extract); bromelain 5000 GDU/g; Mucosave® (prickly pear and olive extract); capsule shell/capsuleschaal: pullulan; maltodextrin; beta-carotene.
Main indication: Intestinal flora
Specific indication: Intestinal barrier
Dosage: 2 capsules per day with a glass of water with a meal.
Recommandations: This dietary supplement is not a substitute for a varied and balanced diet and a healthy lifestyle and is not a medicine. Inform your doctor or pharmacist if you are taking any medicines at the same time. Keep out of reach of children. Store at room temperature in a dry place. Do not exceed the recommended daily dose. Do not dispose of in the natural environment.
Notification number: NUT 3760/113
Posologie (nbr gélules/jour)

Reference 43

Condition: New product

ean13: 5430003465370

Attachments

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Ingredients for Optimal Intestinal Health

MicrobiomeX®: The first patented flavobiotic, widely documented for its effects on the gut and immune system, it has been studied for its role in balancing the microbiome and its ability to support a healthy intestinal environment. This natural extract of orange and grapefruit, rich in flavonoids such as hesperidin and naringin, is metabolized in the colon by the gut microbiome. These compounds are associated with increased production of short-chain fatty acids (SCFAs), particularly butyrate, a key element for the optimal functioning of the intestinal mucosa.[1]
Mucosave®: A 100% natural and innovative plant-based combination, highly concentrated in polyphenols (3.7-4.3%) and polysaccharides (18-28%). The olive contained in this complex contributes to the functions of the intestinal tract, promoting proper digestive function.

Through the synergy of these natural active ingredients, Mucosave® helps maintain a harmonious digestive environment. This natural complex is composed of polysaccharides from prickly pear (Opuntia ficus-indica), known for its ability to adhere to intestinal mucosa, creating a protective layer. Meanwhile, olive biophenols (Olea europaea), such as oleuropein and hydroxytyrosol, are recognized for their active role in the proper functioning of the intestinal tract.[2]

Bromelain: A natural enzyme with a powerful enzymatic activity of 5000 DGU/g, often used to support digestive processes, particularly in the breakdown of dietary proteins. Although not yet backed by a specific health claim, it is widely recognized in literature for its impact on digestion and maintaining healthy mucous membranes.[3]
Beta-Carotene: A precursor to vitamin A, known for its ability to renew tissues, particularly those involved in the intestinal barrier.[4]

FAQ - Everything You Need to Know About Perméavits

How does Perméavits help improve intestinal health?

Perméavits supports intestinal health by acting on several key aspects through its patented ingredients. MicrobiomeX®, a citrus extract rich in flavonoids, is metabolized in the intestine by the microbiome, contributing to the balance of intestinal bacteria and the production of short-chain fatty acids (SCFAs) such as butyrate. These acids play an important role in the proper functioning of the intestinal mucosa, promoting a balanced intestinal environment. Additionally, Mucosave®, which combines Opuntia polysaccharides and Olea europaea biophenols, supports the functions of the intestinal tract. These ingredients are used to maintain an optimal digestive environment and ensure the comfort of intestinal mucosa. Finally, vitamin A, present in the form of beta-carotene in the formula, contributes to the maintenance of normal mucous membranes, which is essential to preserve the integrity of the intestinal barrier.

What is the recommended dosage?

It is recommended to take 2 capsules per day, ideally during meals, with a glass of water. This dosage ensures optimal absorption of the active ingredients and maximizes the benefits for intestinal well-being. For lasting results, it is recommended to use Perméavits regularly. However, if you have specific medical conditions or are taking other treatments, it is always best to consult a healthcare professional to adjust the dosage according to your personal needs.

Is Perméavits suitable for everyone?

Perméavits is suitable for most adults looking to support their digestive health and strengthen their intestinal barrier. However, pregnant or breastfeeding women, as well as individuals undergoing medical treatment, should consult their doctor before starting supplementation. This dietary supplement is designed to meet the needs of people with sensitive intestines, but it is always important to assess whether its ingredients are suitable for your health profile.

How long does it take to feel the benefits of Perméavits?

The benefits of Perméavits can vary from person to person, but some consumers begin to notice an improvement in their digestive comfort after only a few weeks of regular use. Clinical studies on key ingredients like Mucosave® show a reduction in digestive discomfort in less than 4 weeks.[2] For optimal results, it is recommended to continue taking it for at least 8 weeks. It is important to emphasize that adopting a balanced diet and a healthy lifestyle will enhance the beneficial effects of the product.

Can Perméavits be taken with other dietary supplements?

Yes, Perméavits can be combined with other dietary supplements. Its natural ingredients and clean formulation allow it to be paired with other products, such as probiotics or supplements for overall vitality. However, if you are taking multiple supplements, it is always wise to consult a healthcare professional to avoid any potential interactions and ensure that the combination is suitable for your specific needs.

Optimal Protection for Your Intestines

Perméavits is a carefully formulated dietary supplement designed to support intestinal health through a combination of natural and patented ingredients. MicrobiomeX®, a citrus extract rich in flavonoids such as hesperidin and naringin, is metabolized by the intestinal microbiome, contributing to the production of short-chain fatty acids (SCFAs) such as butyrate, which plays a role in the functioning of the intestinal mucosa. Mucosave®, combining prickly pear polysaccharides and olive biophenols, supports the functions of the intestinal tract, promoting a healthy digestive balance. In addition to these active ingredients, Perméavits also includes vitamin A, known to contribute to the maintenance of normal mucous membranes, which strengthens the protection and integrity of the intestinal barrier. Bromelain, an enzyme derived from pineapple with a powerful enzymatic activity of 5000 DGU/g, further enhances digestive support. Suitable for a wide adult population, Perméavits fits perfectly into a daily wellness routine.

Studies

[1] Stevens Y, Rymenant EV, Grootaert C, Camp JV, Possemiers S, Masclee A, Jonkers D. The Intestinal Fate of Citrus Flavanones and Their Effects on Gastrointestinal Health. Nutrients. 2019 Jun 27;11(7):1464. doi: 10.3390/nu11071464. PMID: 31252646; PMCID: PMC6683056.

[2] Alecci U, Bonina F, Bonina A, Rizza L, Inferrera S, Mannucci C, Calapai G. Efficacy and Safety of a Natural Remedy for the Treatment of Gastroesophageal Reflux: A Double-Blinded Randomized-Controlled Study. Evid Based Complement Alternat Med. 2016;2016:2581461. doi: 10.1155/2016/2581461. Epub 2016 Oct 12. PMID: 27818697; PMCID: PMC5080480.

[3] Felton G. et al., Does kinin release by pineapple stem bromelain stimulate production of prostaglandin E&-like compound, Haw. Med.

[4] https://www.anses.fr/fr/content/vitamine-carot%C3%A9no%C3%AFdes-provitaminiques.

[5] Stevens Y et al. (2019) Randomised Clinical Study: Efficacy of MicrobiomeX® on microbiome composition and gut inflammation in healthy overweight individuals

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