EVENING PRIMROSE & BORAGE OIL

Gamma-linolenic acid

This synergy of organic evening primrose and borage oil is appreciated for its richness in gamma-linolenic acid. This polyunsaturated fatty acid of the omega-6 family has properties for the skin, hormonal balance and acts on the modulation of the immune system (autoimmune diseases). GLA, detailed in numerous scientific journals, promotes the synthesis of type 1 prostaglandins (anti-inflammatory) to the detriment of type 2 prostaglandins (pro-inflammatory). The anti-inflammatory actions are mainly recognised in hormonal disorders, such as premenstrual syndrome[1], menopausal discomfort[2], reduction of acne[3] and help in case of eczema[4]. GLA has been clinically studied in other inflammatory conditions such as osteoporosis[5] and in reducing the symptoms of rheumatoid arthritis with a daily GLA intake of 480mg (7 capsules)[6-7]. Finally, the administration of evening primrose and borage oils rich in gamma-linolenic acid to asthmatic patients inhibits the formation of pro-inflammatory leukotrienes [8-9].

[1] Edilberto A Rocha Filho et al; "Essential fatty acids for premenstrual syndrome and their effect on prolactin and total cholesterol levels: a randomized, double-blind, placebo-controlled study"; Reproductive Health 2011, 8:2 doi: 10.1186/1742- 4755-8-2. [2] Farzaneh, F., Fatehi, S., et al. (2013) "The effect of oral evening primrose oil on menopausal hot flashes: a randomized clinical trial". [3] "The efficacy and safety of gamma-linolenic acid in the treatment of acne vulgaris"; Int J Dermatol. 2014; 53(3): e199-200. [4] Morse, N. L., & Clough, P. M. (2006). A meta-analysis of randomized, placebo-controlled clinical trials of evening primrose oil in atopic eczema. [Kruger MC, Coetzer H, et al. "Gamma-linolenic acid and eicosapentaenoic acid in senile osteoporosis". Aging (Milano) 1998 Oct;10(5):385-94. [6] Cameron M & al. Herbal therapy for the treatment of rheumatoid arthritis. Cochrane Database Syst Rev. 2011 Feb 16;2:CD002948. [7] Laposata, M. (1996). "Gamma-linolenic acid treatment of rheumatoid arthritis. A randomized placebo-controlled trial". [8] "The impact of a medical food containing gammalinolenic and eicosapentaenoic acids on asthma management and quality of life in adult asthmatic patients". Curr Med Res Opin. 2008 ; 24(2) : 559-67. [9] "Effect of Borago Officinalis extract on moderate persistent asthma: a phase two, randomized, double-blind, placebo-controlled clinical trial".

Nutritional information