Iron bisglycinate + B6 & B9 vitamins 

Maximum intake of iron bisglycinate and bioavailable vitamins B6 + B9 (Quatrefolic®). This product is perfectly suitable for vegetarians.

Strong iron contributes to :

• Normal cognitive function
• Normal oxygen transport in the body
• Normal formation of red blood cells and haemoglobin
• Cell division
• Normal energy metabolism
• Reduction of fatigue
• Normal functioning of the immune system

Innovative formula composed of iron bisglycinate combined with active vitamin B9 (4th generation - QUATREFOLIC) and active vitamin B6. Iron is involved in the production of haemoglobin, a protein that ensures the transport of oxygen by red blood cells and contributes to the production of enzymes and neurotransmitters that are essential to our body. It prevents certain anaemias (iron deficiency anaemia), stimulates the immune system, resistance to infections and reduces general fatigue (promotes the production of noradrenalin). The added Quatrefolic® B9 is structurally analogous to the reduced and active form of folate. This patented form bypasses the reaction of the enzyme "methyltetrahydrofolate reductase". Unfortunately, mutations in the MTHFR gene affect over 40% of the world's population[1] . This polymorphism is the most common genetic cause of hyperhomocysteinemia leading to health disorders due to lack of methylation (cardiovascular disorders, infertility, depression, etc.)[2]. Pregnant women with MTHFR gene polymorphism have an increased risk of developing complications during pregnancy (low birth weight, pre-eclampsia, hyperactivity of the newborn, etc.) and even miscarriage [3]. Vitamin B9 (Quatrefolic®) is, among other things, recommended during preconception, pregnancy and also lactation [3]. Finally, a meta-analysis has demonstrated the value of vitamin B6 in pregnant and breastfeeding women (apgar scores, birth weight, pre-eclampsia, premature birth, etc.)[4].

Nutritional information

* Recommended Daily Allowance (Directive 2008/100/EC amending -> Decree 08.01.1992)

STUDIES

[1] Ahmed M Abbas, Safaa A Abdelbadee et al. «Efficacité du bis-glycinate ferreux par rapport au sulfate de glycine ferreux dans le traitement de l’anémie ferriprive pendant la grossesse: un essai clinique randomisé en double aveugle» ; Randomized Controlled Trial J Matern Fetal Neonatal Med. 2019 Dec;32(24):4139-4145. [2] Jamil K. Biol Med J 2014; Van der Put N.M.J. et al. Am J Hum Genet 1998; Tsang B.L. et al. A J Clin Nutr 2015; [3] Ulrich C.M., Potter JD. Cancer Epidemiol Biomarkers Prev 2006; Wilcken B. et al. J Med Genet. 2003; Seremak-Mrozikiewicz A et al. Neuro Endocrinol Lett 2010; Botto L.D., Yang Q. Am J Epidemiol 2000; Plumptre et al. Am J Clin Nutr 2015 [4] Rehana A Salam, Nadeem F Zuberi ; Supplémentation en pyridoxine (vitamine B6) pendant la grossesse ou le travail pour les issues maternelles et néonatales; métaanalyse en réseau et une analyse séquentielle d’essais d’essais cliniques randomisés - Cochrane Database Syst Rev. 2015 Jun 3;(6):CD000179.