Active vitamin B12 is recommended for vegetarians and vegans and people with vitamin B12 deficiency [1]. 

Dietary supplement rich in active vitamin B12 :

• Helps reducing fatigue
• Helps maintain normal psychological functions
• Contributes to the normal functioning of the nervous system
• Promotes proper immune function
• Is involved in the normal formation of red blood cells

What is methylcobalamin? 

Methylcobalamin is the most active form of vitamin B12. It contributes, among other things, to cell growth and renewal, to the functioning of the nervous system, to the synthesis of neurotransmitters and red blood cells via hematopoiesis, and to the maintenance of the myelin sheath (the structure surrounding and protecting nerve fibers). Methylcobalamin is also involved in the proper functioning of the cardiovascular system via homocysteine.

What are the causes of a vitamin B12 deficiency?

The majority of vitamin B12 deficiencies result from malabsorption [5] due to the non-dissociation of vitamin B12 from its ligands (dietary proteins and haptocorrin) and a lack of intrinsic factor. The causes are related to a loss of activity in the digestive tract (gastritis, Helicobacter infection, pancreatic insufficiency, intestinal inflammation, medication, etc.). B12 Forte bypasses this assimilation problem by using a pure and bioavailable form of vitamin B12 maximizing its diffusion/passive assimilation in the small intestine.

Nutritional information

* Recommended Daily Allowance (Directive 2008/100/EC amending -> Decree 08.01.1992)

Studies

[1] Dali-Youcef N, Andrès E. Le point sur la carence en vitamine B12 chez l'adulte. Q J Med 2009;102:17-28 
[2] M J Stampfe et al. "Une étude prospective de l'homocystéine plasmatique et du risque d'infarctus du myocarde chez les médecins américains" JAMA. 1992 Aug 19;268(7):877-81; 
[3] J Perry et al. " Étude prospective de la concentration sérique d'homocystéine totale et du risque d'accident vasculaire cérébral chez des hommes britanniques d'âge moyen;" Lancet. 1995 Nov 25;346(8987):13958. 
[4] " Giuseppe Scalabrino et al. "Preuves expérimentales et cliniques du rôle des cytokines et des facteurs de croissance dans la pathogenèse de la leuconeuropathie acquise par carence en cobalamine" Brain Res Rev. 2008 Nov;59(1):42-54. ; 
[5] Angelica Loup-Leuciuc et al. "Carence en vitamine B12. Partie 1 : mise à jour et revue de la littérature"; Med Buccale Chir Buccale Volume 17, Number 3, Août 2011